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      Recombinant Human IL-15
      名稱(chēng) Recombinant Human IL-15
      型號
      更新時(shí)間 2023-09-24
      特點(diǎn) IL-15 細胞因子,刺激T淋巴細胞的增殖和與IL-2許多生物學(xué)性質(zhì)。主要在T細胞IL-15發(fā)揮其生物活性。也很重要的發(fā)展,生存和NK細胞的活化。增加表達IL-15牽連了風(fēng)濕性關(guān)節炎、炎癥性腸病和艾滋病和HTLV-I隸屬于逆轉錄病毒疾病。人類(lèi)IL-15生物活性在小鼠細胞的劑量依賴(lài)性刺激老鼠的CTLL細胞的擴散。重組人類(lèi)IL-15 12.9 kDa蛋白由115個(gè)氨基酸殘基組成。使用所有無(wú)動(dòng)物生產(chǎn)試劑}
      • 詳細內容

      一.產(chǎn)品名稱(chēng):Recombinant Human IL-15/重組IL-15

      二.Catalog Number:AF-200-15

      三.Synonyms:IL-T

      四.Description:

      IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowel disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues. Manufactured using all non-animal reagents.

      五.AA Sequence:

      MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

      六.Source:E.coli

      七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

      八.Biological Activity:

      Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥2 x 106 units/mg.

      九.Cross Reactivity:Monkey, Mouse, Human, Human + Mouse

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